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001 978-981-10-3193-9
003 DE-He213
005 20200811140231.0
007 cr nn 008mamaa
008 161210s2017 si | s |||| 0|eng d
020 _a9789811031939
_9978-981-10-3193-9
024 7 _a10.1007/978-981-10-3193-9
_2doi
050 4 _aQD410-412.5
072 7 _aPNND
_2bicssc
072 7 _aSCI013040
_2bisacsh
072 7 _aPNND
_2thema
082 0 4 _a547.05
_223
100 1 _aShang, Rui.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
245 1 0 _aNew Carbon–Carbon Coupling Reactions Based on Decarboxylation and Iron-Catalyzed C–H Activation
_h[electronic resource] /
_cby Rui Shang.
250 _a1st ed. 2017.
264 1 _aSingapore :
_bSpringer Singapore :
_bImprint: Springer,
_c2017.
300 _aXVII, 216 p. 163 illus., 7 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringer Theses, Recognizing Outstanding Ph.D. Research,
_x2190-5053
505 0 _aIntroduction to Carbon-Carbon Coupling Reactions Based on Decarboxylation and Iron-Catalyzed C-H Activation -- Part I New Carbon-Carbon Bond Formation Methodologies Based on Decarboxylation -- Transition-Metal-Catalyzed Decarboxylation and Decarboxylative Cross-Couplings -- Palladium-Catalyzed Decarboxylative Coupling of Potassium Oxalate Monoester with Aryl and Alkenyl Halides -- Synthesis of Polyfluorobiaryls via Copper-Catalyzed Decarboxylative Couplings of Potassium Polyfluorobenzoates with Aryl Bromides and Iodides -- Palladium-Catalyzed Decarboxylative Couplings of Potassium Polyfluorobenzoates with Aryl Bromides, Chlorides and Triflates -- Construction of C(sp3)-C(sp2) Bonds via Palladium-Catalyzed Decarboxylative Couplings of 2-(2-Azaaryl)acetate Salts with Aryl Halides -- Synthesis of α-Aryl Nitriles and α-Aryl Acetate Esters via Palladium-Catalyzed Decarboxylative Couplings of α-Cyano Carboxylate Salts and Malonate Monoester Salts with Aryl Halides -- Palladium-Catalyzed Decarboxylative Couplings of Nitrophenyl Acetate Salts and Its Derivatives with Aryl Halides -- Palladium-Catalyzed Decarboxylative Benzylation of α-Cyano Aliphatic Carboxylate Salts with Benzyl Electrophiles -- Part II New Carbon-Carbon Bond Formation Methodologies Based on Iron-Catalyzed C-H Activation -- Recent Develpments of Iron-Catalyzed Directed C-H Activation/C-C Bond Formation Reactions.-β-Arylation of Carboxamides via Iron-Catalyzed C(sp3)–H Bond Activation -- Iron-Catalyzed C(sp2)–H and C(sp3)–H Bond Functionalization with Organoboron Compounds.
520 _aThis thesis presents the latest developments in new catalytic C–C bond formation methods using easily accessible carboxylate salts through catalytic decarboxylation with good atom economy, and employing the sustainable element iron as the catalyst to directly activate C–H bonds with high step efficiency. In this regard, it explores a mechanistic understanding of the newly discovered decarboxylative couplings and the catalytic reactivity of the iron catalyst with the help of density functional theory calculation. The thesis is divided into two parts, the first of which focuses on the development of a series of previously unexplored, inexpensive carboxylate salts as useful building blocks for the formation of various C–C bonds to access valuable chemicals. In turn, the second part is devoted to several new C–C bond formation methodologies using the most ubiquitous transition metal, iron, as a catalyst, and using the ubiquitous C–H bond as the coupling partner.
650 0 _aOrganometallic chemistry .
650 0 _aCatalysis.
650 0 _aChemistry, Physical and theoretical.
650 1 4 _aOrganometallic Chemistry.
_0https://scigraph.springernature.com/ontologies/product-market-codes/C19020
650 2 4 _aCatalysis.
_0https://scigraph.springernature.com/ontologies/product-market-codes/C29000
650 2 4 _aTheoretical and Computational Chemistry.
_0https://scigraph.springernature.com/ontologies/product-market-codes/C25007
830 0 _aSpringer Theses, Recognizing Outstanding Ph.D. Research,
_x2190-5053
856 4 0 _uhttps://doi.org/10.1007/978-981-10-3193-9
912 _aZDB-2-CMS
912 _aZDB-2-SXC
942 _cEBK
999 _c202292
_d202292