| 000 | 00388nam a2200121Ia 4500 | ||
|---|---|---|---|
| 999 |
_c199664 _d199664 |
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| 020 | _a9780128127339 | ||
| 040 | _cChemistry | ||
| 100 | _aHaufe, Gunter | ||
| 245 | 0 | _aFluorine in life sciences: pharmaceuticals, medicinal diagnostics, and agrochemicals/ | |
| 260 |
_bElsevier, _c2019. |
||
| 300 | _a686 p. | ||
| 505 | _a1 - Emerging fluorination methods in organic chemistry relevant for life science application 2 - Fluorination patterns in small alkyl groups: their impact on properties relevant to drug discovery 3 - Polyfluorinated scaffolds in drug discovery 4 - Case studies of fluorine in drug discovery 5 - Recent development in fluorinated antibiotics 6 - Fluorosugars as inhibitors of bacterial enzymes 7 - Microbial metabolism of fluorinated drugs 8 - Influence of fluorination on alcohol hydrogen-bond donating properties 9 - Synthesis and applications of backbone-fluorinated amino acids 10 - 19F-Labeled amino acids for NMR structure analysis of membrane-bound peptides 11 - In vivo 19-fluorine magnetic resonance imaging 12 - Fluorine-18 radiolabeling of biologics 13 - Serotonin receptor imaging by 18F-PET 14 - Organoboronates: captors of 18F-fluoride for one-step radiofluorination of biomolecules 15 - Silicon-based 18F-radiopharmaceuticals: from basic SiFA chemistry toward its clinical application 16 - Biorelevant fluorine-containing N-heterocycles 17 - Recent applications of fluorine in crop protection—new discoveries originating from the unique heptafluoroisopropyl group 18 - The role of fluorine in the design of nicotinic acetylcholine receptor (nAChR) competitive modulators | ||
| 650 | _aFluorine--Physiological effect | ||
| 856 | _uhttps://www.sciencedirect.com/science/book/9780128127339 | ||
| 942 | _cEBK | ||