000 01485aam a22003374a 4500
999 _c195395
_d195395
020 _a052180177X
040 _cCUS
082 0 4 _a572.80285
_bDWY/G
100 1 _aDwyer, Rex A.
245 1 0 _aGenomic perl: from bioinformatics basics to working code /
_cRex A. Dwyer
260 _aCambridge, UK ;
_aNew York :
_bCambridge University Press,
_c2003.
300 _axvii, 334 p.
505 _aThe Central Dogma -- DNA and RNA -- Chromosomes -- Proteins -- The Central Dogma -- Transcription and Translation in Perl -- RNA Secondary Structure -- Messenger and Catalytic RNA -- Levels of RNA Structure -- Constraints on Secondary Structure -- RNA Secondary Structures in Perl -- Counting Hydrogen Bonds -- Folding RNA -- Comparing DNA Sequences -- DNA Sequencing and Sequence Assembly -- Alignments and Similarity -- Alignment and Similarity in Perl -- Predicting Species: Statistical Models -- Perl Subroutine Libraries -- Species Prediction in Perl -- Substitution Matrices for Amino Acids -- More on Homology -- Deriving Substitution Matrices from Alignments -- Substitution Matrices in Perl -- The PAM Matrices -- PAM Matrices in Perl -- Sequence Databases -- FASTA Format -- GenBank Format -- GenBank's Feature Locations -- Reading Sequence Files in Perl -- Object-Oriented Programming in Perl -- The SimpleReader Class -- Hiding File Formats with Method Inheritance -- Local Alignment and the BLAST Heuristic -- The Smith-Waterman Algorithm -- The BLAST Heuristic -- Preprocessing the Query String -- Scanning the Target String -- Implementing BLAST in Perl -- Statistics of BLAST Database Searches -- BLAST Scores for Random DNA -- BLAST Scores for Random Residues -- BLAST Statistics in Perl -- Interpreting BLAST Output -- Multiple Sequence Alignment I -- Extending the Needleman-Wunsch Algorithm -- NP-Completeness -- Alignment Merging: A Building Block for Heuristics -- Merging Alignments in Perl -- Finding a Good Merge Order.
650 0 _aPerl (Computer program language)
650 0 _aMolecular biology
_xData processing.
650 0 _aBioinformatics.
942 _cWB16