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020			_a9780195676884
020			_a0195676882
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100			_aChakravarty, Ashim K. _910533
245			_aImmunology and Immunotechnology
260			_aNew Delhi: _bOxford University Press, _c2008.
300			_a592 p.
505			_a1. Immunology: History and Significance 'Cellular' Immunity Versus Humoral Immunity Ehrlich's Hypothesis Other Important Findings Anaphylaxis Transplantation and Tolerance Immunoglobulins Overview of Immunity Scope of Immunology 2. The Immune System Development of the Immune System Primary Lymphoid Organs Secondary Lymphoid Organs 3. Immunoreactive Cells and Receptors Lymphocytes Uniqueness of Lymphocytes and Clonal Selection Theory 4. Cytokines and Regulation General Characteristics of Cytokines Cytokine Types Molecular Mechanism of Regulations Defects in Cytokine Receptors and Diseases Biological Activities of Cytokines Cytokine Secretion by Helper T Cell Subsets Proinflammatory Cytokines Chemokine Family Participation of Cytokines in Inflammatory Response Cytokine Diseases and Therapies 5. Antibody Synthesis and B Cell Activation Antibody Responses Cell Interactions in Antibody Response B Cell Activation Synthesis and Secretion of Immunoglobulins 6. Immunoglobulin Molecules Structure of an Immunoglobulin Molecule: IgC Molecule Immunoglobulin Classes Immunoglobulin Subclasses Immunoglobulin Types Immunoglobulin Superfamily 8 Contents 7. Immunoglobulin and T cell Receptor Genes Immvinoglobulin Genes Multigene Family and Assembly of TCR Genes by V-D-J Joining 8. Antigens Factors Responsible for Immunogenicity Antigenic Determinants (Epitopes) Adjuvant Superantigens 9. Antigen-Antibody Reaction and Diagnostic Procedures Molecular Mechanism of Antigen-Antibody Binding Precipitation Reactions Immunoelectrophoresis Agglutination Radioimmimoassay Immunofluorescence Enzyme-linked Immunosorbent Assay Western Blotting for Identifying Protein and Antibody Ferritin-conjugated Antibodies for Electron Microscopy Ammonium Sulphate Precipitation of Ag-Ab Complex 10. Complement Complement Components Complement Activation Regulation of Complement Activation Complement and Inflammation Complement Deficiencies 11. Major Histocompatibility Complex Histocompatibility Genes Genomic Map of H-2 Complex in the Mouse Minor Histocompatibility Loci HLA Complex in Humans MHC in Different Species Structure of MHC Molecules MHC-Peptide Interaction Expression of MHC Molecules on Different Cell Types Transcriptional Regulation of MHC Expression MHC Molecules and Graft Rejection Why Does MHC Exist in a Cluster? Biological Significance of MHC HLA-Disease Association HLA Typing (Tissue Typing) 12. Cell-mediated Response and Transplantation Types of Cell-mediated Immune Responses T Cell Activation CTL-mediated Cytotoxicity Natural Killer Cell-mediated Cytotoxicity Transplantation Immunology Blood Transfusion 13. Cancer and Immune Responses Characteristics of Tumours and Cancer Cells Cancer Induction and Oncogenes Immune Responses to Tumours Escape Mechanisms of Tumour Immunotherapy for Cancer Conclusion 14. Hypersensitivity Types of Hypersensitivity Type I—IgE-mediated Hypersensitivity Type II—Cytotoxic-type Hypersensitivity Type III Immune Complex-mediated Hypersensitivity Type IV—Delayed-type Hypersensihvity 15. Tolerance and Autoimmunity Tolerance Mechanism of Self-tolerance Termination of Tolerance Autoimmunity 16. Immunodeficiency and AIDS Primary Immunodeficiency Secondary or Acquired Immunodeficiencies Acquired Immunodeficiency Syndrome Hallmark of HIV Infection: Reduction in Number of CD4'^ T Cells 17. Immunity to Pathogens and Vaccines Physical Barriers to Pathogens Viral Infections Immunity to Bacterial Infection Immunity to Fungi Immunity to Parasites Vaccination 18. Techniques used in Immunotechnology Haemagglutination Titre and Assay for Antibody-secreting Cells Separation and Identificanon of Protein or Antigen Hybridoma Technology: Monoclonal Antibodies Antibody Engineering Gene Transfer Technology SCID Mice and SCID-humai Mice Bone Marrow Transplantation Tissue Culture Other Techniques Contributing to Immunotechnology
650			_aImmunology _97085
650			_aImmunotechnology _910536
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