000 02283cam a22002414a 4500
999 _c167787
_d167787
020 _a9780470741856 (hardcover)
020 _a9780470741849 (softcover)
040 _cCUS
082 _a572.8
_bDAL/M
100 1 _aDale, Jeremy
_919764
245 1 0 _aMolecular genetics of bacteria/
_cJeremy W. Dale and Simon Park.
250 _a5th ed.
260 _aChichester, West Sussex, England ;
_bWiley-Blackwell,
_c2010.
300 _axiii, 388 p. :
_bill. ;
_c25 cm.
504 _aIncludes bibliographical references (p. [333]-335) and index.
505 _aNucleic Acid Structure and Function -- Structure of nucleic acids -- DNA -- RNA -- Hydrophobic interactions -- Different forms of the double helix -- Supercoiling -- Denaturation and hybridization -- Orientation of nucleic acid strands -- Replication of DNA -- Unwinding and rewinding -- Fidelity of replication: proof-reading -- Chromosome replication and cell division -- DNA repair -- Mismatch repair -- Excision repair -- Recombination (post-replication) repair -- SOS repair -- Gene expression -- Transcription -- Translation -- Post-translational events -- Gene organization -- Mutation and Variation -- Variation and evolution -- Fluctuation test -- Directed mutation in bacteria? -- Types of mutations -- Point mutations -- Conditional mutants -- Variation due to larger scale DNA alterations -- Extrachromosomal agents and horizontal gene transfer -- Phenotypes -- Restoration of phenotype -- Reversion and suppression -- Complementation -- Recombination -- Mechanisms of mutation -- Spontaneous mutation -- Chemical mutagens -- Ultraviolet irradiation -- Isolation and identification of mutants -- Mutation and selection -- Replica plating -- Penicillin enrichment -- Isolation of other mutants -- Molecular methods -- Regulation of Gene Expression -- Gene copy number -- Transcriptional control -- Promoters -- Terminators, attenuators and anti-terminators -- Induction and repression: regulatory proteins -- Attenuation: trp operon -- Two-component regulatory systems -- Global regulatory systems.
650 0 _aBacterial genetics.
_919765
650 0 _aMicrobial genetics.
_99514
650 0 _aMolecular genetics.
_95129
650 0 _aGenetic engineering.
700 1 _aPark, Simon
_919766
942 _cWB16
_01