000 00365nam a2200145Ia 4500
999 _c145391
_d145391
020 _a8186535039
040 _cCUS
082 _a572.8
_bFRE/E
100 _aFreifelder, David
245 0 _aEssentials of molecular biology /
_cDavid Freifelder; edited by George Malacinski
250 _a2nd ed.
260 _aNew Delhi:
_bPanima,
_c1996.
300 _a478 p.
505 _a1. Systems of and Analytical Approaches to Molecular Biology /George M. Malacinski Bacteria Bacteriophage Yeasts Animal Cells Genetics and Molecular Biology Genetic Analysis of Mutants Rapid Progress in Molecular Biology 2. Macromolecules /George M. Malacinski Chemical Structures of thp Major Classes of Macromolecules Noncovalent Interactions that Determine the Three-dimensional Structures of Proteins and Nucleic Acids Macromoleculc Isolation and Characterization 3.Nucleic Acids Robert Cedergren Physical and Chemical Structure of DNA Alternate DNA Structures Circular and Superhelical DNA Renaturation Hybridization The Structure of RNA Hydrolysis of Nucleic Acids Sequencing Nucleic Acids Synthesis of DNA 4.The Physical Structure of Protein Molecules /Alexandra Newton Basic Features of Protein Molecules The Folding of a Polypeptide Chain The a Helix and BETA Structures Protein Structure Proteins with Subunits Enzymes 5. Macromolecular Interactions and the Structure of Complex Aggregates /George M. Malacinski A Complex DNA Structure: The E. Coli Chromosome Chromosomes and Chromatin Interaction of DNA and Proteins that Recognize a Specific Base Sequence Biological Membranes 6. The Genetic Material /Robert L. Sinsheimer Identification of DNA as the Genetic Material Properties of the Genetic Material RNA as the Genetic Material 7. DNA Replication /Kenneth Marians Semiconservative Replication of Double-stranded DNA Enzymology of DNA Replication DNA Ligase Discontinuous Replication Events in the Replication Fork A Summary of Events at the Replication Fork Initiation of Synthesis at the Leading Strand Bidirectional Replication Replication of Eukaryotic Chromosomes 8. DNA Repair /Philip C. Hanawalt Alterations of DNA Molecules Repair of Incorrect Bases Repair by Direct Reversal Excision Repair Inducible Responses 9. Transcription /John Richardson Enzymatic Synthesis of RNA Transcription Signals Classes of RNA Molecules Transcription in Eukaryotes Means of Studying Intracellular RNA 10. Translation /Joseph Ilan Outline of Translation The Genetic Code The Wobble Hypothesis Polycistronic mRNA Overlapping Genes Polypeptide Synthesis Stages of Polypeptide Synthesis in Prokaryotes Complex Translation Units Antibiotics 11. Mutagenesis, Mutations and Mutants /Thomas Lindahl Types of Mutations Biochemical Basis of Mutants Mutagenesis Mutational Hot Spots Reversion Reversion as a Means of Detecting Mutagens and Carcinogens 12. Plasmids and Transposons /Barry Polisky Plasmid-borne Genes Plasmid Transfer Plasmid DNA Replication Transposable Elements Transposable Elements in Eukaryotes 13. Recombinant DNA and Genetic Engineering: Molecular Tailoring of Genes /Dorothy M. Skinner and Christie A. Holland Plasmids Act as Nature's Interlopers Restriction Enzymes Function as Nature's Pinking Shears Genetic Interlopers; Vectors Function as Vehicles for Transferring Genes Applications of Genetic Engineering Problems and Future of Recombinant DNA 14. Regulation of Gene Activity in Prokaryotes /Sankar L. Adhya Principles of Regulation Transcriptional Regulation Post-Transcriptional Control Control by Proteolysis Feedback Inhibition and Allosteric Control 15. Bacteriophage /David Parma and Larry Gold Steps in the Lytic Life Cycle of a Typical Phage Specific Phage Transducing Phage
700 _aMalacinski, George, ed.
942 _cWB16