TY  - BOOK
AU  - Haufe, Gunter
TI  - Fluorine in life sciences: pharmaceuticals, medicinal diagnostics, and agrochemicals
SN  - 9780128127339
PY  - 2019///
PB  - Elsevier
KW  - Fluorine--Physiological effect
N1  - 1 - Emerging fluorination methods in organic chemistry relevant for life science application

2 - Fluorination patterns in small alkyl groups: their impact on properties relevant to drug discovery

3 - Polyfluorinated scaffolds in drug discovery

4 - Case studies of fluorine in drug discovery

5 - Recent development in fluorinated antibiotics

6 - Fluorosugars as inhibitors of bacterial enzymes

7 - Microbial metabolism of fluorinated drugs

8 - Influence of fluorination on alcohol hydrogen-bond donating properties

9 - Synthesis and applications of backbone-fluorinated amino acids

10 - 19F-Labeled amino acids for NMR structure analysis of membrane-bound peptides

11 - In vivo 19-fluorine magnetic resonance imaging

12 - Fluorine-18 radiolabeling of biologics

13 - Serotonin receptor imaging by 18F-PET

14 - Organoboronates: captors of 18F-fluoride for one-step radiofluorination of biomolecules

15 - Silicon-based 18F-radiopharmaceuticals: from basic SiFA chemistry toward its clinical application

16 - Biorelevant fluorine-containing N-heterocycles

17 - Recent applications of fluorine in crop protection—new discoveries originating from the unique heptafluoroisopropyl group

18 - The role of fluorine in the design of nicotinic acetylcholine receptor (nAChR) competitive modulators

UR  - https://www.sciencedirect.com/science/book/9780128127339
ER  -