Haufe, Gunter <br/><br/>
Fluorine in life sciences: pharmaceuticals, medicinal diagnostics, and agrochemicals/ 

 -  Elsevier,  2019. 
 - 686 p. 
<br/><br/>1 - Emerging fluorination methods in organic chemistry relevant for life science application<br/><br/>2 - Fluorination patterns in small alkyl groups: their impact on properties relevant to drug discovery<br/><br/>3 - Polyfluorinated scaffolds in drug discovery<br/><br/>4 - Case studies of fluorine in drug discovery<br/><br/>5 - Recent development in fluorinated antibiotics<br/><br/>6 - Fluorosugars as inhibitors of bacterial enzymes<br/><br/>7 - Microbial metabolism of fluorinated drugs<br/><br/>8 - Influence of fluorination on alcohol hydrogen-bond donating properties<br/><br/>9 - Synthesis and applications of backbone-fluorinated amino acids<br/><br/>10 - 19F-Labeled amino acids for NMR structure analysis of membrane-bound peptides<br/><br/>11 - In vivo 19-fluorine magnetic resonance imaging<br/><br/>12 - Fluorine-18 radiolabeling of biologics<br/><br/>13 - Serotonin receptor imaging by 18F-PET<br/><br/>14 - Organoboronates: captors of 18F-fluoride for one-step radiofluorination of biomolecules<br/><br/>15 - Silicon-based 18F-radiopharmaceuticals: from basic SiFA chemistry toward its clinical application<br/><br/>16 - Biorelevant fluorine-containing N-heterocycles<br/><br/>17 - Recent applications of fluorine in crop protection—new discoveries originating from the unique heptafluoroisopropyl group<br/><br/>18 - The role of fluorine in the design of nicotinic acetylcholine receptor (nAChR) competitive modulators<br/> 
<br/><br/><label>ISBN: </label>9780128127339 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Fluorine--Physiological effect