TY - BOOK AU - Rupp, Bernhard TI - Biomolecular crystallography: principles, practice, and application to structural biology SN - 9780815340812 U1 - 572.36 PY - 2010/// CY - U.S.A PB - Garland Science KW - Crystallography KW - Biomolecules-Structure KW - Molecular Dynamics N1 - Includes Glossary and Index; PART I: FROM SEQUENCE TO CRYSTALS 1. Introduction: Preparing Your Study 2. Protein Structure 3. Protein Crystallization 4. Proteins for Crystallography PART II: FUNDAMENTALS OF PROTEIN CRYSTALLOGRAPHY 5. Crystal Geometry 6. Diffraction Basics 7. Statistics and Probability in Crystallography PART III: FROM CRYSTALS TO DATA 8. Instrumentation and Data Collection PART IV: DETERMINING YOUR STRUCTURE 9. Reconstruction of Electron Density and the Phase Problem 10. Experimental Phasing 11. Non-Crystallographic Symmetry and Molecular Replacement 12. Model Building and Refinement PART V: MAKING SENSE OF YOUR STRUCTURE 13. Structure Validation, Analysis, and Presentation ER -