TY - BOOK AU - edited by Gadamasetti, Kumar G. TI - Process chemistry in the pharmaceutical industry SN - 9780824719814 U1 - 615.19 PY - 1999/// CY - New York PB - Library of congress KW - Chemical Processes KW - Pharmaceutical Chemistry N1 - Overview 1: Process Chemistry in the Pharmaceutical Industry: An Overview Strategy 2: Process Research and Development Strategy for Accelerated Projects Case Studies 3: A Practical Synthesis of Ifetroban Sodium 4: Synthesis of 5-Lipoxygenase Inhibitors 5: Chemistry of Vitamin D: A Challenging Field for Process Research 6: A Highly Optimized and Concise Large Scale Synthesis of a Purine Bronchodilator 7 Ontazolast: The Evolution of a Procss 8 Dilevalol Hydrochloride: Development of a Commercial Process 9 Design and Development of Practical Syntheses of LY228729, a Potent 5HT1a Receptor Agonist 10 Process Research and Development of CGS 19755, an NMDA Antagonist 11 Route Evaluation for the Production of (R)-Levoprotiline, 12 The Process Research and Development of DuPont Merck's Cyclic Urea Diols, A New Class of HIV Protease Inhibitors 13 Practical Enantio- and Diastereo-selective Processes for Azetidinones 14 Synthesis of the Common Lactone Moiety of HMG-CoA Reductase Inhibitors Enzymatic Intervention and Phase Transfer Catalysis 15 Chemistry, Biocatalysis and Engineering: An Interdisciplinary Approach to the Manufacture of the Benzodiazepine Drug Candidate LY 300164 16 Benefits and Challenges of Applying Phase-Transfer Catalysis Technology in the Pharmaceutical Industry Asymmetric Synthesis and Enantioselectivity 17 Enantioselective Synthesis: The Optimum Process 18 Practical Catalysts for Asymmetric Synthesis: Ligands from Natural Sugars for Rh-Catalyzed Asymmetric Synthesis of D- and L- Amino Acids 19 Chiral (Salen)Mn(III) Complexes in Asymmetric Epoxidations: Practical Synthesis of cis-Aminoindanol and Its Application to Enantiopure Drug Synthesis Drug Substance Final Form and Process Safety 20 Chemical Development of the Drug Substance Solid Form 21 The Basic Principles of Thermal Process Safety: Towards a Better Communication Between Safety Experts and Process Chemists Design of Experiments and Automation 22 Using Factorial Experiments in the Development of Process Chemistry 23 Laboratory Automation in Chemical Development ER -