TY - BOOK AU - Fano, A. TI - Lethal laws: animal lasting human health & environmental policy U1 - 179.4 PY - 1998/// CY - London PB - Zed Books N1 - 1. Fatal connection: cancer and animal testing The politics of cancer /y The debate over the causes of cancer /8 Turning to animal testing for answers /9 A brief history of toxicological testing on animals /ii 2. The numbers game: how animal-based toxicological risk assessment works The US National Toxicology Program /19 Toxicological risk assessment: a brief overview /20 How the NT? animal testing program works /21 The species and numbers of animals used in toxicity tests /21 How animal testing is performed /24 How animal data are extrapolated to humans /27 How animal data are used within the regulatory framework /28 3. For the public good? Debunking the animal testing myth The arguments in favor of animal testing 744 The arguments against /49 The difficulty of inter-species extrapolation /50 False positives/false negatives /57 Different testing methods produce different results /60 The artificiality of laboratory life 764 The 'dirt' on 'germfree' animals 766 Humans make mistakes 768 The animal tests have never been validated 769 A criticism of specific tests and methods 774 Humanit arian considerations 778 Time and cost of testing 784 4. Human health at risk Criticism of the risk assessment process /103 Getting away with murder /106 Why animal tests do not protect humans from toxins /109 Particular chemicals as examples /i 12 The laws and guidelines governing animal testing requirements /122 The business of animal testing: who profits? /131 5. Toxicological testing without using animals The 'alternatives' concept /153 Examples of non-animal toxicological testing methods /153 The alternatives scam: refinement and reduction vs. full replacement /168 The validation issue: a barrier to a full and immediate ban on animal testing /179 Some success stories /186 6. Reclaiming our health and our humanity: strategies for change The need for a new paradigm /209 Chemical bans /214 The path to revolution: forms of public protest /217 The activist struggle in the face of economic globalization /219 Environmentalists and animal advocates: a necessary union /220 Legislation /222 The False Claims Act: a legal challenge to the US government /223 The future of toxicity testing without animals /225 ER -