TY - BOOK AU - King, Frank D. TI - Medicinal chemistry: Principles and practice SN - 0854046313 U1 - 572 PY - 2002/// CY - London PB - Royal KW - Pharmaceutical chemistry. KW - Chimie pharmaceutique. KW - Pharmacologie N1 - Drug-receptor interactions / Rob Leurs -- An introduction to ion channels / Brian Cox -- Intercellular targets / Eric Hunt [and others] -- Enzyme inhibitors / David A. Roberts and Walter H.J. Ward -- Biological evaluation of novel compounds / Gary W. Price, Graham J. Riley and Derek N. Middlemiss -- Pharmacokinetics / Phillip Jeffrey -- Drug metabolism / Stephen E. Clarke -- Toxicology in the drug discovery process / Susan M. Evans, Elisabeth George and C. Westmoreland -- Chemical development / Paul Smith -- Physicochemical properties / Han van de Waterbeemd -- Quantitative structure. : Activity relationships / David J. Livingstone -- Computational chemistry and target structure / Colin Edge -- Patent medicine / Bill Tyrrell -- An introduction to molecular biology / Ralph Rapley and Robert J. Slater -- Strategy and tactics in drug discovery / Frank D. King -- Combinatorial chemistry : tools for the medicinal chemist / Morag A.M. Easson and David C. Rees -- The identification of selective 5-HT2c receptor antagonists : a new approach to the treatment of depression and anxiety / Steven M. Bromidge -- The identification of the HIV protease inhibitor. Saquinavir / Frank D. King -- Discovery of vioxx (rofecoxib) / Frank D. King -- NK1 receptor antagonists / Chris Swain ER -