TY - BOOK AU - Nogrady, Thomas TI - Medicinal chemistry: A molecular and biochemical approach SN - 0195104560 U1 - 615.19 PY - 2005/// CY - New York PB - Oxford University Press KW - Pharmaceutical chemistry KW - Chemistry, Pharmaceutical KW - Drug Design N1 - PART A: GENERAL MOLECULAR PRINCIPLES OF DRUG DESIGN; 1. Basic Principles of Drug Design I: Drug Molecules: Structure and Properties; 2. Basic Principles of Drug Design II: Receptors: Structures and Properties; 3. Basic Principles of Drug Design III: Designing Drug Molecules to Fit Receptors; PART B: BIOCHEMICAL CONSIDERATIONS IN DRUG DESIGN; 4. Messenger Targets for Drug Action I: Neurotransmitters and Their Receptors; 5. Messenger Targets for Drug Action II: Hormones and Their Receptors; 6. Messenger Targets for Drug Action III: Immunomodulators and Their Receptors; 7. Nonmessenger Targets for Drug Action I: Endogenous Cellular Structures; 8. Nonmessenger Targets for Drug Action II: Endogenous Macromolecules; 9. Nonmessenger Targets for Drug Action III: Exogenous "Nonself" Pathogens; Appendix A: Drugs arranged by pharmacologic activity ER -