Drug-Like Properties /
Material type: TextPublication details: Elsevier, 2016ISBN: 9780128010761Online resources: Click here to access onlineItem type | Current library | Call number | Status | Date due | Barcode | Item holds |
---|---|---|---|---|---|---|
e-Books | Central Library, Sikkim University | Not for loan | E-171 |
Chapter 1 - Introduction
Chapter 2 - Benefits of Property Assessment and Good Drug-Like Properties
Chapter 3 - In Vivo Environments Affect Drug Exposure
Chapter 4 - Prediction Rules for Rapid Property Profiling from Structure
Chapter 5 - Lipophilicity
Chapter 6 - pKa
Chapter 7 - Solubility
Chapter 8 - Permeability
Chapter 9 - Transporters
Chapter 10 - Blood-Brain Barrier
Chapter 11 - Metabolic Stability
Chapter 12 - Plasma Stability
Chapter 13 - Solution Stability
Chapter 14 - Plasma and Tissue Binding
Chapter 15 - Cytochrome P450 Inhibition
Chapter 16 - hERG Blocking
Chapter 17 - Toxicity
Chapter 18 - Integrity and Purity
Chapter 19 - Pharmacokinetics
Chapter 20 - Lead Properties
Chapter 21 - Strategies for Integrating Drug-Like Properties into Drug Discovery
Chapter 22 - Methods for Profiling Drug-Like Properties: General Concepts
Chapter 23 - Lipophilicity Methods
Chapter 24 - pKa Methods
Chapter 25 - Solubility Methods
Chapter 26 - Permeability Methods
Chapter 27 - Transporter Methods
Chapter 28 - Blood-Brain Barrier Methods
Chapter 29 - Metabolic Stability Methods
Chapter 30 - Plasma Stability Methods
Chapter 31 - Solution Stability Methods
Chapter 32 - CYP Inhibition Methods
Chapter 33 - Plasma and Tissue Binding Methods
Chapter 35 - Toxicity Methods
Chapter 36 - Integrity and Purity Methods
Chapter 37 - Pharmacokinetic Methods
Chapter 38 - Diagnosing and Improving Pharmacokinetic Performance
Chapter 39 - Prodrugs
Chapter 40 - Effects of Properties on Biological Assays
Chapter 41 - Formulation
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