Comprehensive biophysics: biophysics techniques for structural characterization of macromolecules/ edited by Edward H. Egelma

VOLUME 4 Molecular Motors and Motility
4.1 Introduction YE Goldman and EM Ostap
General Theoretical Considerations
4.2 Microscopic Reversibility and Free-Energy Transduction by Molecular Motors and
Actin
Pumps RD Astumian
4.3 Structure and Dynamic States of Actin Filaments EH Egelman
4.4 Actin Filament Nucleation and Elongation Dominguez and Namgoong
4.5 Mechanical Properties of Actin Networks KE Kasza and DAWeitz
Microtubules
4.6 Tubulin and Microtubule Structure: Mechanistic Insights into Dynamic Instability and Its
Biological Relevance E Nogales and G Alushin
4.7 Force Generation by Dynamic Microtubule Polymers EL Grishchuk, JR Mcintosh,
Myosin
MI Molodtsov, and Fl Ataullakhanov
4.8 Myosin Motors: Structural Aspects and Functionality MPreller and DJ Manstein
4.9 Myosin Motors: Kinetics of Myosin YE Goldman and EM Ostap
4.10 Single Molecule Fluorescence Techniques for Myosin Takagi and JR Sellers
Muscle
4.11 Cell-Based Studies of the Molecular Mechanism of Muscle Contraction MIrving 191
4.12 Spectroscopic Probes of Muscle Proteins DD Thomas, JM Muretta, BA Colson, RN Mello,
and D Kast
4.13 Thin Filament Regulation MA Geeves
4.14 Smooth Muscle and Myosin Regulation KM Trybus

vi Contents
Non-Muscle Motility
4.15 Intracellular Transport: Relating Single-Molecule Properties to In Vivo
Function GT Shubeita and SP Gross 287
4.16 Mechanical Forces in Mitosis S Dumont and TJ Mitchison 298
Kinesin
4.17 Kinesin Structure and Biochemistry SP Gilbert and HS Sardar 321
4.18 Kinesin Single-Molecule Mechanics BE Clanq' and SM Block 345
Dynein
4.19 Cytoplasmic Dynein: Its ATPase Cycle and ATPase-dependent Structural Changes T Kon,
T Shima, and K Sutoh 360
4.20 Axonemal Motility R Kamiya 377
Nucleic Acid Motors
4.21 The Ribosome BS Cooperman 393
4.22 Viral DNA Packaging Motors CL Hetherington, JR Moffitt, PJ Jardine, and C Bustamante 420