Exploring Immunology: concepts and evidence/ Gordon MacPherson; & Jon Austyn

Cover; Related Titles; Title Page; Copyright; Dedication; Preface; A Note to the Reader; Introduction; 1 Introduction; 2 Immune Responses; 3 Infection and Immunity; 4 Immunopathology and Immunotherapy; 5 Exploring Immunology; Chapter 1: The Immune System; 1.1 Introduction; 1.2 Host Defence Against Infection; 1.3 Anatomical Basis of Immunity; 1.4 Cellular Basis of Immunity; 1.5 Molecular Basis of Immunity; 1.6 Immune Responses and Disease; Chapter 2: Infection and Immunity; 2.1 Introduction; 2.2 Pathogens and Infectious Disease; 2.3 Host Defence Against Infection. 2.4 Infection and Immunity in Action2.5 Immunity and Vaccines; Chapter 3: Functional Anatomy of the Immune System; 3.1 Introduction; 3.2 Natural Barriers; 3.3 Functional Anatomy of Innate Immunity; 3.4 Functional Anatomy of Adaptive Immunity; 3.5 Development of Blood Cells and Organs of Immunity; 3.6 Stem Cell and Gene Therapy; Chapter 4: Innate Immunity; 4.1 Introduction; 4.2 Induction of Innate Immunity; 4.3 Tissue-Resident Cells of Innate Immunity; 4.4 Recruited Effectors of Innate Immunity; 4.5 Haematopoiesis and Myeloid Cells; 4.6 Vaccines and Adjuvants. Chapter 5: T Cell-Mediated Immunity5.1 Introduction; 5.2 Major Histocompatibility Complex (MHC) and Antigen Presentation; 5.3 T Lymphocyte Activation; 5.4 Effector and Memory Functions of T Cells in Infection; 5.5 T Cell Development and Selection; 5.6 Adoptive Cell Therapy; Chapter 6: Antibody-Mediated Immunity; 6.1 Introduction; 6.2 Antibody Structure and Function; 6.3 B Cell Responses; 6.4 B Cell Memory, Antibodies and Long-Term Resistance to Re-Infection; 6.5 B Cell Differentiation and Selection; 6.6 Therapeutic Antibodies; Chapter 7: Immunity, Disease and Therapy; 7.1 Introduction. 7.2 What are the Mechanisms of Tissue Damage Caused by the Immune System?7.3 Why Do We Make Harmful Immune Responses to Harmless Antigens?; 7.4 Immunopathology and Therapy in Action; 7.5 Transplantation Immunology; 7.6 Tumour Immunity; 7.7 Conclusions; Answers to the Questions; Further Study Questions; Index.