Process chemistry in the pharmaceutical industry/ edited by Kumar G. Gadamasetti.

Overview
1: Process Chemistry in the Pharmaceutical Industry: An Overview

Strategy
2: Process Research and Development Strategy for Accelerated Projects

Case Studies
3: A Practical Synthesis of Ifetroban Sodium
4: Synthesis of 5-Lipoxygenase Inhibitors
5: Chemistry of Vitamin D: A Challenging Field for Process Research
6: A Highly Optimized and Concise Large Scale Synthesis of a Purine Bronchodilator
7 Ontazolast: The Evolution of a Procss
8 Dilevalol Hydrochloride: Development of a Commercial Process
9 Design and Development of Practical Syntheses of LY228729, a Potent 5HT1a Receptor Agonist
10 Process Research and Development of CGS 19755, an NMDA Antagonist
11 Route Evaluation for the Production of (R)-Levoprotiline, 12 The Process Research and Development of DuPont Merck's Cyclic Urea Diols, A New Class of HIV Protease Inhibitors
13 Practical Enantio- and Diastereo-selective Processes for Azetidinones
14 Synthesis of the Common Lactone Moiety of HMG-CoA Reductase Inhibitors

Enzymatic Intervention and Phase Transfer Catalysis
15 Chemistry, Biocatalysis and Engineering: An Interdisciplinary Approach to the Manufacture of the Benzodiazepine Drug Candidate LY 300164
16 Benefits and Challenges of Applying Phase-Transfer Catalysis Technology in the Pharmaceutical Industry

Asymmetric Synthesis and Enantioselectivity
17 Enantioselective Synthesis: The Optimum Process
18 Practical Catalysts for Asymmetric Synthesis: Ligands from Natural Sugars for Rh-Catalyzed Asymmetric Synthesis of D- and L- Amino Acids
19 Chiral (Salen)Mn(III) Complexes in Asymmetric Epoxidations: Practical Synthesis of cis-Aminoindanol and Its Application to Enantiopure Drug Synthesis

Drug Substance Final Form and Process Safety
20 Chemical Development of the Drug Substance Solid Form
21 The Basic Principles of Thermal Process Safety: Towards a Better Communication Between Safety Experts and Process Chemists

Design of Experiments and Automation
22 Using Factorial Experiments in the Development of Process Chemistry
23 Laboratory Automation in Chemical Development