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Mass spectrometry in drug discovery/ Rossi, David T.

Material type: Text

TextPublication details: New York: Marcel and Dekker, 2002Edition: 1st edDescription: 420 pISBN: 9780824706074DDC classification: 543.0873

Contents:

I Introduction 1 Demand for drug discovery today 2 The impact of atmospheric pressure ionization II Instrumentation 3 A mass spectrometry primer III Experimental strategies 4 Ion chemistry and fragmentation 5 The LC/MS experiment 6 Sample preparation and handling for LC/MS in drug discovery IV Applications 7 Mass spectrometry in combinatorial chemistry 8 Drug hydrophobicity and transport 9 The mass spectrometer in drug metabolism 10 Mass spectrometry-assisted applications of stable-labeled compounds in pharmacokinetic and drug metabolism studies 11 Cassette dosing in drug discovery 12 Applications of microdialysis/mass spectrometry to drug discovery 13 Future directions for mass spectrometry in drug discovery

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Holdings
Item type	Current library	Call number	Status	Notes	Date due	Barcode	Item holds
General Books Science Library	Science Library, Sikkim University Science Library General Section	543.0873 ROS/M (Browse shelf(Opens below))	Available	Books For SU Science Library		P01163

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I Introduction
1 Demand for drug discovery today
2 The impact of atmospheric pressure ionization

II Instrumentation
3 A mass spectrometry primer

III Experimental strategies
4 Ion chemistry and fragmentation
5 The LC/MS experiment
6 Sample preparation and handling for LC/MS in drug discovery

IV Applications
7 Mass spectrometry in combinatorial chemistry
8 Drug hydrophobicity and transport
9 The mass spectrometer in drug metabolism
10 Mass spectrometry-assisted applications of stable-labeled compounds in pharmacokinetic and drug metabolism studies
11 Cassette dosing in drug discovery
12 Applications of microdialysis/mass spectrometry to drug discovery
13 Future directions for mass spectrometry in drug discovery

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