Essentials of molecular biology / David Freifelder and George Malacinski

By: Freifelder, DavidContributor(s): Malacinski, George MMaterial type: TextTextPublication details: New Delhi: Panima, 1996Edition: 2nd edDescription: 478 pISBN: 8186535039DDC classification: 572.8
Contents:
1. Systems of and Analytical Approaches to Molecular Biology /George M. Malacinski Bacteria Bacteriophage Yeasts Animal Cells Genetics and Molecular Biology Genetic Analysis of Mutants Rapid Progress in Molecular Biology 2. Macromolecules /George M. Malacinski Chemical Structures of thp Major Classes of Macromolecules Noncovalent Interactions that Determine the Three-dimensional Structures of Proteins and Nucleic Acids Macromoleculc Isolation and Characterization 3.Nucleic Acids Robert Cedergren Physical and Chemical Structure of DNA Alternate DNA Structures Circular and Superhelical DNA Renaturation Hybridization The Structure of RNA Hydrolysis of Nucleic Acids Sequencing Nucleic Acids Synthesis of DNA 4.The Physical Structure of Protein Molecules /Alexandra Newton Basic Features of Protein Molecules The Folding of a Polypeptide Chain The a Helix and BETA Structures Protein Structure Proteins with Subunits Enzymes 5. Macromolecular Interactions and the Structure of Complex Aggregates /George M. Malacinski A Complex DNA Structure: The E. Coli Chromosome Chromosomes and Chromatin Interaction of DNA and Proteins that Recognize a Specific Base Sequence Biological Membranes 6. The Genetic Material /Robert L. Sinsheimer Identification of DNA as the Genetic Material Properties of the Genetic Material RNA as the Genetic Material 7. DNA Replication /Kenneth Marians Semiconservative Replication of Double-stranded DNA Enzymology of DNA Replication DNA Ligase Discontinuous Replication Events in the Replication Fork A Summary of Events at the Replication Fork Initiation of Synthesis at the Leading Strand Bidirectional Replication Replication of Eukaryotic Chromosomes 8. DNA Repair /Philip C. Hanawalt Alterations of DNA Molecules Repair of Incorrect Bases Repair by Direct Reversal Excision Repair Inducible Responses 9. Transcription /John Richardson Enzymatic Synthesis of RNA Transcription Signals Classes of RNA Molecules Transcription in Eukaryotes Means of Studying Intracellular RNA 10. Translation /Joseph Ilan Outline of Translation The Genetic Code The Wobble Hypothesis Polycistronic mRNA Overlapping Genes Polypeptide Synthesis Stages of Polypeptide Synthesis in Prokaryotes Complex Translation Units Antibiotics 11. Mutagenesis, Mutations and Mutants /Thomas Lindahl Types of Mutations Biochemical Basis of Mutants Mutagenesis Mutational Hot Spots Reversion Reversion as a Means of Detecting Mutagens and Carcinogens 12. Plasmids and Transposons /Barry Polisky Plasmid-borne Genes Plasmid Transfer Plasmid DNA Replication Transposable Elements Transposable Elements in Eukaryotes 13. Recombinant DNA and Genetic Engineering: Molecular Tailoring of Genes /Dorothy M. Skinner and Christie A. Holland Plasmids Act as Nature's Interlopers Restriction Enzymes Function as Nature's Pinking Shears Genetic Interlopers; Vectors Function as Vehicles for Transferring Genes Applications of Genetic Engineering Problems and Future of Recombinant DNA 14. Regulation of Gene Activity in Prokaryotes /Sankar L. Adhya Principles of Regulation Transcriptional Regulation Post-Transcriptional Control Control by Proteolysis Feedback Inhibition and Allosteric Control 15. Bacteriophage /David Parma and Larry Gold Steps in the Lytic Life Cycle of a Typical Phage Specific Phage Transducing Phage
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General Books General Books Central Library, Sikkim University
General Book Section 		572.8 FRE/E (Browse shelf(Opens below)) Available P00020
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1. Systems of and Analytical Approaches to Molecular Biology /George M. Malacinski
Bacteria
Bacteriophage
Yeasts
Animal Cells
Genetics and Molecular Biology
Genetic Analysis of Mutants
Rapid Progress in Molecular Biology

2. Macromolecules /George M. Malacinski
Chemical Structures of thp Major Classes of
Macromolecules
Noncovalent Interactions that Determine the
Three-dimensional Structures of Proteins and
Nucleic Acids
Macromoleculc Isolation and Characterization

3.Nucleic Acids Robert Cedergren
Physical and Chemical Structure of DNA
Alternate DNA Structures
Circular and Superhelical DNA
Renaturation
Hybridization
The Structure of RNA
Hydrolysis of Nucleic Acids
Sequencing Nucleic Acids
Synthesis of DNA

4.The Physical Structure of Protein Molecules /Alexandra Newton
Basic Features of Protein Molecules
The Folding of a Polypeptide Chain
The a Helix and BETA Structures
Protein Structure
Proteins with Subunits
Enzymes

5. Macromolecular Interactions and the Structure of Complex Aggregates /George M. Malacinski
A Complex DNA Structure: The E. Coli
Chromosome
Chromosomes and Chromatin
Interaction of DNA and Proteins that Recognize a Specific Base Sequence
Biological Membranes

6. The Genetic Material /Robert L. Sinsheimer
Identification of DNA as the Genetic Material
Properties of the Genetic Material
RNA as the Genetic Material

7. DNA Replication /Kenneth Marians
Semiconservative Replication of Double-stranded DNA
Enzymology of DNA Replication
DNA Ligase
Discontinuous Replication
Events in the Replication Fork
A Summary of Events at the Replication Fork
Initiation of Synthesis at the Leading Strand
Bidirectional Replication
Replication of Eukaryotic Chromosomes

8. DNA Repair /Philip C. Hanawalt
Alterations of DNA Molecules
Repair of Incorrect Bases
Repair by Direct Reversal
Excision Repair
Inducible Responses

9. Transcription /John Richardson
Enzymatic Synthesis of RNA
Transcription Signals
Classes of RNA Molecules
Transcription in Eukaryotes
Means of Studying Intracellular RNA

10. Translation /Joseph Ilan
Outline of Translation
The Genetic Code
The Wobble Hypothesis
Polycistronic mRNA
Overlapping Genes
Polypeptide Synthesis
Stages of Polypeptide Synthesis in Prokaryotes
Complex Translation Units
Antibiotics

11. Mutagenesis, Mutations and Mutants /Thomas Lindahl
Types of Mutations
Biochemical Basis of Mutants
Mutagenesis
Mutational Hot Spots
Reversion
Reversion as a Means of Detecting Mutagens and Carcinogens

12. Plasmids and Transposons /Barry Polisky
Plasmid-borne Genes
Plasmid Transfer
Plasmid DNA Replication
Transposable Elements
Transposable Elements in Eukaryotes

13. Recombinant DNA and Genetic Engineering: Molecular Tailoring of Genes /Dorothy M. Skinner and Christie A. Holland
Plasmids Act as Nature's Interlopers
Restriction Enzymes Function as Nature's Pinking Shears
Genetic Interlopers; Vectors Function as Vehicles for Transferring Genes
Applications of Genetic Engineering
Problems and Future of Recombinant DNA

14. Regulation of Gene Activity in Prokaryotes /Sankar L. Adhya
Principles of Regulation
Transcriptional Regulation
Post-Transcriptional Control
Control by Proteolysis
Feedback Inhibition and Allosteric Control

15. Bacteriophage /David Parma and Larry Gold
Steps in the Lytic Life Cycle of a Typical Phage
Specific Phage
Transducing Phage

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