Computational Methods for Processing and Analysis of Biological Pathways
Bezerianos, Anastasios.
Computational Methods for Processing and Analysis of Biological Pathways [electronic resource] / by Anastasios Bezerianos, Andrei Dragomir, Panos Balomenos. - 1st ed. 2017. - VIII, 87 p. 11 illus. in color. online resource. - SpringerBriefs in Computer Science, 2191-5768 . - SpringerBriefs in Computer Science, .
Introduction -- Networks and Pathways in Systems Pharmacology -- Time Varying Methods for Pathway and Sub-Pathway Analysis -- Identification of Differentially Expressed Pathways and Sub-Pathways.
This work offers a guided walkthrough of one of the most promising research areas in modern life sciences, enabling a deeper understanding of involved concepts and methodologies via an interdisciplinary view, focusing on both well-established approaches and cutting-edge research. Highlighting what pathway analysis can offer to both the experimentalist and the modeler, the text opens with an introduction to a general methodology that outlines common workflows shared by several methods. This is followed by a review of pathway and sub-pathway based approaches for systems pharmacology. The work then presents an overview of pathway analysis methods developed to model the temporal aspects of drug- or disease-induced perturbations and extract relevant dynamic themes. The text concludes by discussing several state-of-the-art methods in pathway analysis, which address the important problem of identifying differentially expressed pathways and sub-pathways.
9783319538686
10.1007/978-3-319-53868-6 doi
Bioinformatics.
Systems biology.
Computational Biology/Bioinformatics.
Systems Biology.
QH324.2-324.25
570.285
Computational Methods for Processing and Analysis of Biological Pathways [electronic resource] / by Anastasios Bezerianos, Andrei Dragomir, Panos Balomenos. - 1st ed. 2017. - VIII, 87 p. 11 illus. in color. online resource. - SpringerBriefs in Computer Science, 2191-5768 . - SpringerBriefs in Computer Science, .
Introduction -- Networks and Pathways in Systems Pharmacology -- Time Varying Methods for Pathway and Sub-Pathway Analysis -- Identification of Differentially Expressed Pathways and Sub-Pathways.
This work offers a guided walkthrough of one of the most promising research areas in modern life sciences, enabling a deeper understanding of involved concepts and methodologies via an interdisciplinary view, focusing on both well-established approaches and cutting-edge research. Highlighting what pathway analysis can offer to both the experimentalist and the modeler, the text opens with an introduction to a general methodology that outlines common workflows shared by several methods. This is followed by a review of pathway and sub-pathway based approaches for systems pharmacology. The work then presents an overview of pathway analysis methods developed to model the temporal aspects of drug- or disease-induced perturbations and extract relevant dynamic themes. The text concludes by discussing several state-of-the-art methods in pathway analysis, which address the important problem of identifying differentially expressed pathways and sub-pathways.
9783319538686
10.1007/978-3-319-53868-6 doi
Bioinformatics.
Systems biology.
Computational Biology/Bioinformatics.
Systems Biology.
QH324.2-324.25
570.285